Ensembl Database

The Ensembl database is a comprehensive source for genome information. It stores details about genes, transcripts, and proteins from many species. This skill lets you look up gene IDs, fetch DNA or protein sequences, and see how genetic variants affect genes. It is useful for researchers who need to translate between different naming systems like RefSeq, HGNC, or UniProt.

You can start by entering a gene symbol such as TP53. The tool will resolve it to a stable Ensembl ID. Then you can get the full gene structure including exons. You can also map the ID to other databases. The default species is human. The tool will warn you if it uses a default or non-standard assembly.

All queries go through helper scripts that follow rate limits automatically. The output is saved to files and a summary is shown on screen. If you need an older genome assembly like GRCh37 you can specify it with a flag. This makes it easy to work with different genome versions.