Genomic data analysis can be slow and complex. polars-bio makes it fast and simple. It is built for scientists and analysts who work with DNA sequences and genomic intervals.
The library uses Polars DataFrames to perform operations like overlap, merge, and coverage. It can read and write BED, VCF, and BAM files. Large datasets are handled with streaming and cloud storage support. It is many times faster than older tools like bioframe.
polars-bio works as a drop-in for bioframe workflows. It gives you two ways to write code. You can use functions or chain methods on DataFrames. It also supports SQL queries on genomic data files.
Global
mkdir -p ~/.claude/skills/polars-bioProject
mkdir -p .claude/skills/polars-bioSource Repository
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